{"id":3071,"date":"2022-10-05T13:26:01","date_gmt":"2022-10-05T13:26:01","guid":{"rendered":"https:\/\/www.lanierpharma.com\/?p=1938"},"modified":"2026-04-10T09:01:08","modified_gmt":"2026-04-10T07:01:08","slug":"could-the-induction-of-trained-immunity-by-%ce%b2-glucan-serve-as-a-defence-against-covid-19","status":"publish","type":"post","link":"https:\/\/www.lanierpharma.com\/en\/could-the-induction-of-trained-immunity-by-%ce%b2-glucan-serve-as-a-defence-against-covid-19\/","title":{"rendered":"Could the induction of trained immunity by \u03b2-Glucan serve as a defence against COVID-19?\u00a0"},"content":{"rendered":"<p><strong>Anne Geller, Jun Yan<\/strong><\/p>\n\n\n\n<p><em>Immunol. 2020 Jul 14;11:1782. doi: 10.3389\/fimmu.2020.01782. Ecollection20202<\/em><\/p>\n\n\n\n<p>As the SARS-CoV-2 virus wreaks havoc on populations, primary care infrastructures and economies around the world, finding ways to protect healthcare workers and boost immune responses in the general population, while waiting for a vaccine to definitively eradicate the infection, seems a priority.&nbsp;<\/p>\n\n\n\n<p>Recent studies show that innate immunity may possess a form of memory, called Trained Immunity (TRIM) and that certain substances such as \u03b2-Glucan, with a direct stimulatory action on the immune response, may also behave as a training agent for innate immunity, resulting in more robust immune responses, when cells of this immune system come into contact with a secondary heterologous stimulus.&nbsp;<\/p>\n\n\n\n<p>Understanding the exact mechanism of the immune response to SARS-CoV-2 will likely guide therapeutic and preventive interventions in the future. It will also be very important to understand why some patients develop a hyperinflammatory syndrome, as this will determine prevention and treatment strategies.&nbsp;<\/p>\n\n\n\n<p>It has been shown that oral \u03b2-Glucan can be an efficient, cost-effective and safe way to support the immune response to SARS-CoV-2 and prevent severe clinical pictures.<\/p>","protected":false},"excerpt":{"rendered":"<p>Anne Geller, Jun Yan Immunol. 2020 Jul 14;11:1782. doi: 10.3389\/fimmu.2020.01782. Ecollection20202 As the SARS-CoV-2 virus wreaks havoc on populations, primary care infrastructures and economies around the world, finding ways to protect healthcare workers and boost immune responses in the general population, while waiting for a vaccine to definitively eradicate the infection, seems a priority.&nbsp; Recent [&hellip;]<\/p>\n","protected":false},"author":17,"featured_media":1094,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[199],"tags":[],"class_list":["post-3071","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-inmunoproteccion-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Could the induction of trained immunity serve against COVID-19?\u00a0<\/title>\n<meta name=\"description\" content=\"As SARS-CoV-2 wreaks havoc on populations, primary 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